Starting ONFI (clobazam)
Your healthcare provider may start with a lower dose of ONFI and increase it as your loved one's body adjusts to it. It may take some time to find the dose that is appropriate. Knowing about ONFI and how and when to take it is important to getting off to a good start.
ONFI should be taken exactly as your healthcare provider says. Make sure to tell your healthcare provider how your loved one is feeling and whether he or she is experiencing any side effects. Do not stop giving ONFI to your loved one without talking to your healthcare provider first.
Before your loved one starts ONFI, tell your healthcare provider if he or she has:
- Liver or kidney problems
- Lung problems (respiratory disease)
- Depression, mood problems, or suicidal thoughts or behavior
- Any other medical conditions
- Birth control medicine use: ONFI may cause your loved one's birth control medicine to be less effective
- Plans to become pregnant or is pregnant.* ONFI may harm the unborn baby
- An infant she is nursing.* Your healthcare provider should decide if your loved one will take ONFI or breastfeed. You should not do both.
ONFI is available in 2 different forms, including: 10-mg and 20-mg scored tablets & 2.5-mg/mL oral suspension.
How is ONFI taken?
ONFI should be taken exactly as your healthcare provider says. Your healthcare provider will tell you how much should be taken and when. He or she may also change the dose if needed.
ONFI is usually taken twice a day.
ONFI tablets can be taken whole, broken in half along the score, or crushed and mixed in applesauce.
ONFI tablets and oral suspension can be taken with or without food.
Tell your healthcare provider about all the medicines your loved one is taking, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking ONFI with certain other medicines can cause side effects or affect how well they work.
- ONFI comes in 10-mg and 20-mg scored tablets, as well as 2.5-mg/mL oral suspension
- To break a tablet in half, press on the line or "score"
- ONFI oral suspension comes in a berry flavor
- It should be kept at room temperature
- Shake the bottle of ONFI oral suspension well right before you take each dose
- ONFI oral suspension should be kept in its original bottle in an upright position and used within 90 days of first opening the bottle. After 90 days, safely throw away any ONFI oral suspension that has not been used
Please read the Instructions for Use at the end of the Medication Guide for information on the right way to use ONFI oral suspension.
- Your healthcare provider may start with a lower dose of ONFI and increase it as your loved one's body adjusts to it. It may take some time to find the appropriate dose that is right for your loved one
- Do not change the dose without first talking to your healthcare provider
- Do not stop giving ONFI to your loved one without talking to your healthcare provider first. Stopping ONFI all at once can cause serious problems
- If your loved one has taken too much ONFI, call your healthcare provider right away. You may also want to go to the nearest hospital emergency room
- If your loved one has any side effects that bother him or her, tell your healthcare provider. You should also do this if side effects do not go away. This can sometimes happen when your healthcare provider adjusts the dose to find the one that works best
- Be sure to tell their healthcare provider how your loved one is feeling
*If your loved one becomes pregnant while taking ONFI, tell their healthcare provider as well. You may need to sign up with the North American Antiepileptic Drug Pregnancy Registry. This can be done by calling 1-888-233-2334. The purpose of the registry is to learn more about the safety of antiepileptic drugs during pregnancy