About ONFI® (clobazam)
ONFI has been shown to reduce [[tooltip]seizures] associated with Lennox-Gastaut syndrome (LGS) in people 2 years of age or older. It’s an [[tooltip]adjunctive] treatment, which means that it’s added to a treatment plan that includes other [[tooltip]antiepileptic drugs (AEDs)]. Benzodiazepines, like ONFI, can cause severe drowsiness, breathing problems (respiratory depression), coma, and death when taken with opioid medicines.
In the largest clinical study to date of adults and children with LGS, adding ONFI was shown to lower the number of seizures people had each week. The study evaluated 238 participants, and the goal was to find out if adding ONFI to a person’s current treatment plan could lower his or her number of [[tooltip]atonic], [[tooltip]tonic], or [[tooltip]myoclonic seizures.] At all doses, treatment with ONFI reduced how often people had drop seizures each week.
In this study, the most common side effects were sleepiness or tiredness, drooling, constipation, cough, pain with urination, fever, acting aggressive, being angry or violent, difficulty sleeping, slurred speech, and problems breathing.
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[[center-mobile]Starting ONFI]
[[color-grey]ONFI Scored Tablets can be broken in half or administered whole]
[[color-grey]ONFI Oral Suspension 2.5 mg/mL provides dosing in a liquid formulation]
[[center-mobile]Ask for ONFI by name]
Generic versions of clobazam are available. If you or your loved one prefer taking Brand-name ONFI, talk to your healthcare provider and ask for ONFI to be specified in your prescription.
DISPENSE AS WRITTEN (DAW)
If your healthcare provider decides that ONFI is what is best for you or your loved one, the provider may include the words “Dispense as Written” (DAW) on the prescription or follow your state’s rule for prescribing branded products.
If your doctor has prescribed ONFI, make sure to check the medicine when you receive it to determine if you have been given brand-name ONFI as prescribed by your doctor or if the pharmacy has substituted a generic version of clobazam. If you have a question about this, contact your doctor or pharmacist.
[[center-mobile]HOW IS ONFI TAKEN?]
- ONFI should be taken exactly as your healthcare provider says. Your healthcare provider will tell you how much should be taken and when. He or she may also change the dose if needed
- ONFI is usually taken twice a day
- ONFI tablets can be taken whole, broken in half along the score, or crushed and mixed in applesauce
- ONFI tablets and oral suspension can be taken with or without food
- Tell your healthcare provider about all the medicines your loved one is taking, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking ONFI with certain other medicines can cause side effects or affect how well they work